Our umbrella review that revealed no links between serotonin and depression has caused shock waves among the general public, but been dismissed as old news by psychiatric opinion leaders. This disjunction begs the questions of why the public have been fed this narrative for so long, and what antidepressants are actually doing if they are…
Summary: I respond to some of the points in the recent Rolling Stone article and correct the many inaccuracies and distortions. Ignoring is no longer working, so champions of big Pharma and mainstream psychiatry have gone into attack mode. The strategy is to undermine the messenger (me) in order to neutralise the message. In this…
Summary TL;DR For decades people have been told that depression is caused by a serotonin deficiency. This was the rationale behind the introduction of the SSRI (Selective Serotonin Reuptake Inhibitor) antidepressants in the 1990s, which were thought to work by boosting low levels of serotonin. Our research shows no evidence of low serotonin in depression,…
Our new review of serotonin research collated research from six different areas. We looked at research on serotonin levels in body fluids, levels of the main metabolite (breakdown product) of serotonin in the cerebro-spinal fluid (brain fluid), serotonin receptors, the serotonin transporter protein (the protein that removes serotonin from the synapse where it is active-…
In this blog I look at the functions of the mental health system as they relate to the economic and social structure of society using Marx’s economic framework. I conclude that the mental health system is essentially a system of care and control, that is legitimated by the concept of mental illness and that plays…
Original article: Vincenzo’s commentary: Part 1 Part 2 For those who have not read my original article, it traces the social functions of the mental health system and its relationship to Capitalism. It suggests the principal functions of this system consist of the public provision of care for those who cannot care for themselves, and…
Psychedelics are an increasingly fashionable medical treatment, but are they anything other than a powerful form of snake oil, or a recreational experience? Do they have any objective health benefits? Can we be confident they are safe? These questions need answering urgently as the number of people being enticed or persuaded to have these drugs is increasing. Here I draw attention to some of the issues raised by the current popularity of these drugs.
In this blog I reflect on what has and has not changed in the field of psychiatric drug treatment in the years between the first and newly published second edition of the Straight Talking Introduction to Psychiatric Drugs.
Summary My historical study of the Essex asylum, just outside London, which was recently published in Psychological Medicine, finds that those who were admitted showed significant disturbances of behaviour or evidence of organic disease. Almost two thirds of those who had psychological, as opposed to organic, disorders were discharged recovered or improved (mostly recovered). The…
We are told that long-term antipsychotic treatment reduces the risk of someone having a ‘relapse’ of schizophrenia or psychosis. What ‘relapse’ actually refers to in the studies that are supposed to establish this has not been examined though. Our recent study of relapse definitions, published in Schizophrenia Research, shows that there is no consistent or…
Joanna Moncrieff 